Rheumatoid arthritis and Interleukin-32
نویسندگان
چکیده
منابع مشابه
Interleukin 6 and Rheumatoid Arthritis
Interleukin-6 (IL-6) is a representative cytokine featuring pleiotropic activity and redundancy. A transient synthesis of IL-6 contributes to host defense against infectious agents and tissue injuries by inducing acute phase reactions and immunological and hematopoietic responses. However, uncontrolled persistent production of IL-6 may lead to the development of several immune-mediated diseases...
متن کاملEffects of leukotriene B4 on interleukin-32, interferon-γ and chemokines in rats with rheumatoid arthritis
The objective of this study was to investigate the effects of leukotriene B4 (LTB4) on the expression of interleukin-32 (IL-32) interferon-γ (IFN-γ) and chemokine monocyte chemoattractant protein (MCP-1) and macrophage inhibitory protein (MIP-1α) in rheumatoid arthritis (RA). The rat model of RA collagen induced-arthritis (CIA) was established. The levels of LTB4, interleukin-32, IFN-γ and chem...
متن کاملInterleukin-7 in rheumatoid arthritis.
Recent data from several groups demonstrate high levels of IL-7 in the joints of RA patients, but much lower levels in OA. In contrast, circulating levels of IL-7 in RA remain a point of debate. IL-7 has many roles in T cell, dendritic cell and bone biology in humans. Reduced levels of circulating IL-7 probably underlie a number of the dysfunctions associated with circulating T cells in RA and ...
متن کاملClinical significance of interleukin-32 expression in patients with rheumatoid arthritis.
OBJECTIVE To explore the clinical significance of interleukin (IL)-32 in the treatment of rheumatoid arthritis (RA) patients and analyze the correlations of IL-32 with C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and rheumatoid factor (RF). METHODS A total of 97 patients with RA and 36 patients with non-RA connective tissue diseases (CTD) were included. The mRNA levels of I...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Immunology
سال: 2007
ISSN: 0911-4300,1349-7413
DOI: 10.2177/jsci.30.398